RESEARCH STUDIES
Formulated for your body. Validated by research.
Since 2010, we’ve set out to formulate the most comprehensive and effective Foundational Nutrition supplement.
Our driving belief? High-quality ingredients combined with healthy gut function could improve the body’s ability to absorb and actually use essential nutrients.
RESEARCH TIMELINE
Setting a new standard in research
Our in-house team of doctors, scientists, and researchers worked with third-party experts to conduct a set of scientific studies and further validate the benefits of AG1. We followed a universally acknowledged hierarchy of scientific rigor, looking beyond ingredient data to test our complete formula and validate the synergy of how ingredients work together.
01 — CLINICAL TRIAL RESULTS
Clinical Trial
A double-blind, randomized, placebo-controlled trial. We monitored 30 healthy adults ages 21-49 over 1 month, measuring the digestive impact of AG1 through stool samples. Research was conducted with a third-party expert to validate and mitigate bias.
AG1 was shown to enrich the gut microbiome, more than doubling the levels of healthy bacteria known to bolster digestion.¹*
2.9x
increase in healthy bacteria in the gut.¹
WHY THIS MATTERS
These healthy bacteria work together to break down food and are known to alleviate bloating, promote digestive regularity, and aid in digestive comfort long term.*
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2.9x
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03 — OBSERVATIONAL STUDY RESULTS
Observational Study
A single-arm study conducted with 35 healthy adults ages 25-48. We measured how participants reported feeling and behaving in different increments over the course of 3 months, and validated the data with a third-party clinical research organization to mitigate bias.
With regular use over 3 months, AG1 was seen to positively impact feelings of calm, energy, and improved digestion.¹
At 1 month¹
80%
of participants noticed less gas & bloating
85%
of participants noticed their bowel movements were more regular
97%
of participants felt more energy
At 3 months+
94%
of participants felt more calm
97%
of participants noticed fewer cravings throughout the day
97%
of participants felt digestion improved
WHY IT MATTERS
Internal changes aren't always felt. By giving your body the routine nutrients it needs, you’re able to experience benefits that build each day.*
“We intentionally designed AG1 to deliver a diverse spectrum of essential daily nutrients with pre and probiotics to support the gut, in a powder form that’s easier for your body to digest than a tablet.”*
Dr. Ralph Esposito
ND, LAc — Functional Medicine, Chief Science & Nutrition Officer
Our research team
Peer-reviewed research
In addition to sharing our results, we collaborate with other experts and researchers in the scientific community to publish research in peer-reviewed scientific journals, helping to lead the discourse on the complex and crucial role nutrition plays in overall health.
NUTRIENTS
Foundational Nutrition: Implications for Human Health
Human nutrition, and what can be considered “ideal” nutrition, is a complex, multi-faceted topic which many researchers and practitioners deliberate. While some attest that basic human nutrition is relatively understood, it is undeniable that a global nutritional problem persists.
FRONTIERS
Nutrient synergy: definition, evidence, and future directions
Nutrient synergy refers to the concept that the combined effects of two or more nutrients working together have a greater physiological impact on the body than when each nutrient is consumed individually.
NUTRACEUTICALS
The Novel Synbiotic, AG1®, Increases Short-Chained Fatty Acid Production in the Simulator of Human Intestinal Microbial Ecosystem (SHIME) Model®
Recently, there is growing usage of prebiotics and probiotics as dietary supplements due to their purported health benefits. AG1® (AG1) is a novel foundational nutrition supplement which contains vitamins, minerals, phytonutrients, wholefood concentrates, adaptogens, and functional mushrooms.
APPLIED BIOSCIENCE
AG1®, a Novel Synbiotic, Demonstrates Superior Mineral Bioaccessibility and Bioavailability Compared to a Tablet Multivitamin and Mineral Supplement Using an In Vitro Model of the Upper Gastrointestinal Tract
While traditional multivitamin and mineral (MVM) supplements generally come in tablet form, new powder forms of MVM supplements are available with theoretically higher bioavailability relative to tablet MVM supplements. which contains vitamins, minerals, phytonutrients, wholefood concentrates, adaptogens, and functional mushrooms.
CURRENT ISSUES IN MOLECULAR BIOLOGY
AG1® Induces a Favorable Impact on Gut Microbial Structure and Functionality in the Simulator of Human Intestinal Microbial Ecosystem® Model
Considering previous experimental data on AG1 and the growing evidence that various phytochemicals can act as prebiotics, the primary objective of the current experiment was to detail the specific effects of AG1 on gut microbial community composition by observing changes in community structure and function.