RESEARCH STUDIES

Formulated for your body. Validated by research.

Since 2010, we’ve set out to formulate the most comprehensive and effective Foundational Nutrition supplement.

Our driving belief? High-quality ingredients combined with healthy gut function could improve the body’s ability to absorb and actually use essential nutrients.

RESEARCH TIMELINE

Setting a new standard in research

Our in-house team of doctors, scientists, and researchers worked with third-party experts to conduct a set of scientific studies and further validate the benefits of AG1. We followed a universally acknowledged hierarchy of scientific rigor, looking beyond ingredient data to test our complete formula and validate the synergy of how ingredients work together.

01 — CLINICAL TRIAL RESULTS

Clinical Trial

A double-blind, randomized, placebo-controlled trial. We monitored 30 healthy adults ages 21-49 over 1 month, measuring the digestive impact of AG1 through stool samples. Research was conducted with a third-party expert to validate and mitigate bias.

AG1 was shown to enrich the gut microbiome, more than doubling the levels of healthy bacteria known to bolster digestion.¹*

2.9x

increase in healthy bacteria in the gut.¹

WHY THIS MATTERS

These healthy bacteria work together to break down food and are known to alleviate bloating, promote digestive regularity, and aid in digestive comfort long term.*

1 In a double-blind, randomized, placebo-controlled clinical trial assessing 30 healthy adults ages 21-49 over the course of 1 month.

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2.9x

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1 In a double-blind, randomized, placebo-controlled clinical trial assessing 30 healthy adults ages 21-49 over the course of 1 month.

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1 In a double-blind, randomized, placebo-controlled clinical trial assessing 30 healthy adults ages 21-49 over the course of 1 month.

03 — OBSERVATIONAL STUDY RESULTS

Observational Study

A single-arm study conducted with 35 healthy adults ages 25-48. We measured how participants reported feeling and behaving in different increments over the course of 3 months, and validated the data with a third-party clinical research organization to mitigate bias.

With regular use over 3 months, AG1 was seen to positively impact feelings of calm, energy, and improved digestion.¹

At 1 month¹

80%

of participants noticed less gas & bloating

85%

of participants noticed their bowel movements were more regular

97%

of participants felt more energy

At 3 months+

94%

of participants felt more calm

97%

of participants noticed fewer cravings throughout the day

97%

of participants felt digestion improved

WHY IT MATTERS

Internal changes aren't always felt. By giving your body the routine nutrients it needs, you’re able to experience benefits that build each day.*

1 In a single-arm observational study conducted on 35 healthy adults ages 25-48 assessing the self-perceived efficacy of AG1 over 3 months.

“We intentionally designed AG1 to deliver a diverse spectrum of essential daily nutrients with pre and probiotics to support the gut, in a powder form that’s easier for your body to digest than a tablet.”*

Dr. Ralph Esposito

ND, LAc — Functional Medicine, Chief Science & Nutrition Officer

Peer-reviewed research

In addition to sharing our results, we collaborate with other experts and researchers in the scientific community to publish research in peer-reviewed scientific journals, helping to lead the discourse on the complex and crucial role nutrition plays in overall health.

NUTRIENTS

Foundational Nutrition: Implications for Human Health

Human nutrition, and what can be considered “ideal” nutrition, is a complex, multi-faceted topic which many researchers and practitioners deliberate. While some attest that basic human nutrition is relatively understood, it is undeniable that a global nutritional problem persists.

Read paper

FRONTIERS

Nutrient synergy: definition, evidence, and future directions

Nutrient synergy refers to the concept that the combined effects of two or more nutrients working together have a greater physiological impact on the body than when each nutrient is consumed individually.

Read paper

NUTRACEUTICALS

The Novel Synbiotic, AG1®, Increases Short-Chained Fatty Acid Production in the Simulator of Human Intestinal Microbial Ecosystem (SHIME) Model®

Recently, there is growing usage of prebiotics and probiotics as dietary supplements due to their purported health benefits. AG1® (AG1) is a novel foundational nutrition supplement which contains vitamins, minerals, phytonutrients, wholefood concentrates, adaptogens, and functional mushrooms.

Read paper

APPLIED BIOSCIENCE

AG1®, a Novel Synbiotic, Demonstrates Superior Mineral Bioaccessibility and Bioavailability Compared to a Tablet Multivitamin and Mineral Supplement Using an In Vitro Model of the Upper Gastrointestinal Tract

While traditional multivitamin and mineral (MVM) supplements generally come in tablet form, new powder forms of MVM supplements are available with theoretically higher bioavailability relative to tablet MVM supplements. which contains vitamins, minerals, phytonutrients, wholefood concentrates, adaptogens, and functional mushrooms.

Read paper

CURRENT ISSUES IN MOLECULAR BIOLOGY

AG1® Induces a Favorable Impact on Gut Microbial Structure and Functionality in the Simulator of Human Intestinal Microbial Ecosystem® Model

Considering previous experimental data on AG1 and the growing evidence that various phytochemicals can act as prebiotics, the primary objective of the current experiment was to detail the specific effects of AG1 on gut microbial community composition by observing changes in community structure and function.

Read paper

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